Promethazine with codeine syrup is indicated for your short term aid of coughs and upper respiratory indicators affiliated with allergy or perhaps the prevalent cold.
Anticholinergics – Concomitant use of other agents with anticholinergic Houses really should be carried out with caution.
Codeine: A study in rats and rabbits described no teratogenic effect of codeine administered over the duration of organogenesis in doses starting from five to one hundred twenty mg/kg. Inside the rat, doses in the one hundred twenty-mg/kg stage, inside the toxic range with the Grownup animal, were being affiliated with an increase in embryo resorption at some time of implantation.
In case you are prescribed this medication on an everyday program and overlook a dose, take it as soon as you remember. Whether it is close to the time of the following dose, skip the missed dose. Just take your following dose within the common time. Usually do not double the dose to catch up.
Promethazine shouldn't be used by youngsters youthful than 2 yrs since it may well bring about really serious (potentially deadly) sluggish/shallow respiration. This issue has happened Despite having regular doses With this age group.
Clearance may very well be decreased as well as the metabolites may accumulate to A great deal increased plasma levels in people with renal failure compared to individuals with regular renal perform.
Even though the threat of habit in almost any specific is unknown, it may occur in individuals appropriately prescribed Promethazine HCl and Codeine Phosphate Oral Alternative. Habit can arise at suggested dosages and In the event the drug is misused or abused. Dangers are greater in sufferers with a private or loved ones history of substance abuse (such as drug or alcohol abuse or dependancy) or mental ailment (e.g., key depression).
Patients need to be suggested to evaluate promethazine with codeine syrup with an exact measuring product. A home teaspoon is not an correct measuring gadget and could lead on to overdosage, especially when a 50 % a teaspoon is measured.
Bluish lips or skin chills clay-coloured stools chilly sweats confusion cough darkish urine lower within the frequency of urination reduce while in the urine quantity diarrhea hard or troubled breathing problem in passing urine (dribbling) dizziness dizziness, faintness, or lightheadedness when obtaining up from lying or sitting down position fast, pounding, or irregular heartbeat or pulse emotion of heat fever headache high fever hives or welts, itching, or rash improved sweating irregular, quick or sluggish, or shallow respiration big, hive-like swelling within the confront, eyelids, lips, tongue, throat, palms, legs, toes, or intercourse organs lack of appetite loss of bladder control nausea noisy respiratory not respiration distressing urination pale or blue lips, fingernails, or pores and skin rectal bleeding redness in the facial area, neck, arms, and occasionally, upper chest redness of the pores and skin looking at, Listening to, or experience factors that aren't there seizures severe muscle mass stiffness shakiness while in the legs, arms, or hands tummy pain sweating tightness within the chest tiredness trembling or shaking in the palms or toes disagreeable breath odor abnormal tiredness or weakness unusually pale skin vomiting of blood yellow eyes or skin Get Promethazine codeine syrup unexpected emergency assist immediately if any of the following signs and symptoms of overdose come about:
The following laboratory checks could possibly be afflicted in people who're obtaining therapy with promethazine hydrochloride.
g., amiodarone, quinidine) could end in an increase in codeine plasma concentrations as well as a lessen in active metabolite morphine plasma focus which could result in an analgesic efficacy reduction or indicators of opioid withdrawal.
Having said that, this influence is not dependable and may be offset by an increased fee of cervical dilation, which has a tendency to shorten labor. Keep an eye on neonates exposed to opioids throughout labor for indications of excessive sedation and respiratory depression.
Opioid analgesics and antitussives, including codeine, one of several Lively elements in Promethazine HCl and Codeine Phosphate Oral Remedy, really should not be Employed in clients with acute febrile disease connected to effective cough or in clients with Continual respiratory disorder the place interference with ability to distinct the tracheobronchial tree of secretions might have a deleterious effect on the affected individual’s respiratory perform.
Fall off any unused narcotic medication in a drug choose-again site right away. If you do not Have got a drug get-back again place in your area, flush any unused narcotic medicine down the rest room.